Subscriber Recap – Day 1, Midday Report from Cannes
As we break for lunch here in Cannes, I want to share a midday recap of this morning’s next two sessions — both packed with insight, nuance, and clinical edge. This is where longevity medicine gets tactical.
Dr. Craig Koniver: Resilience, Hormones, and Peptides in Practice
Dr. Craig Koniver of South Carolina opened the session with a practical, patient-forward approach to peptide therapy. His message was simple: use what works — and sometimes that means using multiple peptides at once.
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At Concierge Medical, we routinely guide the use of peptides as part of comprehensive programs, but Dr. Koniver emphasized the flexibility of combining 2, 3, even 5 peptides simultaneously, especially for resilience and recovery.
He walked through key distinctions:
Ipamorelin vs. Sermorelin: Dr. Koniver favors ipamorelin for its specificity and clean profile. I still find sermorelin useful for broader pituitary engagement. As he said, different strokes for different folks — and I agree.
PDA: A peptide many are now using in place of BPC-157, given the FDA’s limitations on compounded BPC. Despite the acronym, it’s no public display of affection — it’s a new tool in the inflammation and tissue support toolbox.
SS-31 and MOTs-C: Mitochondrial peptides continue to gain attention. SS-31 remains one of the most exciting therapeutic targets in mitochondrial medicine.
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What I appreciated was his emphasis on cortisol regulation. Too often villainized, cortisol is essential — when used correctly. His “readiness and resilience” framework made a strong case: morning cortisol peaks are normal and necessary; evening cortisol must fall to allow repair.
His broader philosophy? Get people feeling better fast. That’s not the same as skipping foundational work — it’s a patient-centric model that prioritizes momentum in healing.
At my practice, I prefer to build the scaffold first: correct deficiencies, balance energy, rewire circadian inputs. Different routes, same goal. Are you read to see where the real power in GLP-1 medications are? Keep reading!
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